MedWorm Celiac News

Abstract  Lymphocytic colitis (LC) is a disease of unknown aetiology. Among other pathogenetic possibilities, an abnormal reaction to a luminal antigen has been discussed. To clarify this fact, we characterized the inflammatory infiltrate in LC and compared it with the Th1 response-related coeliac disease (CD). Biopsies from 10 LC and 10 CD patients were analyzed by immunohistochemistry for detection of T-bet, the master regulator of Th1 response and its antagonist GATA-3 in T cells employing double labellings. In LC, 10–20% of intraepithelial lymphocytes (IEL) expressed GATA-3 and the remaining T-bet, whereas in CD, all IEL were T-bet-positive. The T cells in the lamina propria of LC (65–70% CD4+; 30–35% CD8+) showed a mixed expression pattern of T-bet and GATA-3. Th...

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Your body has two “brains.” You know about the one in your head, of course, but there’s also one in your gut. This one decides what’s considered food and what isn’t. It knows what you need for nutrition. Your “gut brain” processes the antigens (molecules recognized by your system) and has a memory of what it’s supposed to digest, what should just pass through, and what needs to be destroyed. Problems start when you eat something foreign to your gut. You see, the food industry tells you that processed foods, grain, wheat, and bread are “good” for you. Even the national food pyramid says most of your daily intake should come from grains. But, what the food industry doesn’t know (or doesn’t tell you) is that your gut doesn’t know what to do with the grain pr...

Contrast-enhanced MRI dynamic evaluation of the bowel wall can effectively (more) (Source: AuntMinnie.com Headlines)

Study findings confirm that celiac disease patients have a similar risk for colorectal cancer to the general population. (Source: MedWire News - Gastroenterology)

Study findings confirm that celiac disease patients have a similar risk for colorectal cancer to the general population. (Source: MedWire News - Oncology)

In this issue of the Gastrointestinal Endoscopy, Mangiavillano et al remind us that the lesion of celiac disease is patchy and suggest that the diagnosis can be missed if biopsy samples from the duodenal bulb are not taken. They report their single-center, prospective study in 47 children with “clinical and serological indicators of the disease.” Each patient underwent EGD with 4 biopsy specimens obtained from the duodenal bulb and 4 from the descending duodenum. One pathologist read the biopsy results blinded to the clinical data. (Source: Gastrointestinal Endoscopy)

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Even though she is obsessed with food and has a nutrition degree, Jessica Meyer struggled for a long time before she was diagnosed with Celiac disease and adopted a gluten-free diet. Jessica's blog includes her original gluten-free recipes, as well as new gluten-free menu options, and product and company information specific to the Austin, Texas local community. Click to read now (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)

Medical terminology can be confusing for many patients, especially children. Have you ever suffered a medical nightmare like this? “Patient displays an acute communicable disease with an incubation period of 2 or 3 weeks and caused by herpesvirus, usually found in children. Manifestations include coryza, fever, malaise, and headache, followed in 2 or 3 days by the eruption of macular vesicles.” Chances are you have. The above paragraph is just a complicated description of a common childhood virus: chicken pox. In most cases doctors are happy to act as medical translators for their patients— explaining complicated medical terminology in every day language— but when it comes to written material, many medical publications rely heavily on industry jargon. It can be intimidati...

Abstract: Background: Although videocapsule endoscopy images are helpful in the evaluation of celiac disease, their interpretation is subjective. Quantitative disease markers could assist in determining the extent of villous atrophy and response to treatment.Method: Capsule endoscopy images were acquired from celiac patients with small bowel pathology (N=11) and from control patients (N=10). Image resolution was 576×576 pixels in dimension, 256 grayscale levels, and had a 2s−1 frame rate. Pixel brightness and image texture were measured over 10×10 pixel subimages and then averaged for 56×56 subimages per frame. Measurements were obtained at five locations from proximal to distal small intestine in each patient. At each location, measurements were calculated using 200 consecutive image...

Children with celiac disease have higher than normal levels of the oxidative DNA damage biomarkers urinary 8-oxodG and 8-oxoGua, regardless of their diet, report researchers. (Source: MedWire News - Pediatrics)

Children with celiac disease have higher than normal levels of the oxidative DNA damage biomarkers urinary 8-oxodG and 8-oxoGua, regardless of their diet, report researchers. (Source: MedWire News - Gastroenterology)

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Children with celiac disease have higher than normal levels of the oxidative DNA damage biomarkers urinary 8-oxodG and 8-oxoGua, regardless of their diet, report researchers. (Source: MedWire News - Oncology)

(Source: Tissue Antigens)

Content Type Journal ArticleDOI 10.1007/s11739-010-0442-1Authors Elisa Romagnoli, Unit of Internal Medicine II, University Hospital of Modena, Via del Pozzo 71, 41100 Modena, ItalyElena Boldrini, Unit of Internal Medicine II, University Hospital of Modena, Via del Pozzo 71, 41100 Modena, ItalyAntonello Pietrangelo, Unit of Internal Medicine II, University Hospital of Modena, Via del Pozzo 71, 41100 Modena, Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)

(Source: BMJ Online First)

Gluten-free foods are a boon to people with celiac disease, wheat allergies or gluten sensitivity. But the notion that this diet can help people lose weight or avoid carbohydrates is a myth. (Source: WSJ.com: Health)

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With a prevalence as high as 1 in 100, chances are you are seeing patients with undiagnosed celiac disease in your practice. Dr. David Johnson explains the latest diagnostic and treatment strategies. Medscape Gastroenterology (Source: Medscape Today Headlines)

Can we assume that patients with celiac disease who are following a gluten-free diet have achieved mucosal healing? Should these patients undergo regular testing? Medscape Gastroenterology (Source: Medscape Today Headlines)

This article is not available freely or via NHS Athens username and password. NHS professionals are advised to check their local library to access the fulltext of this journal. Note: This article has been included in the Specialist Collection as it is a systematic review published in a reputable journal in the field.  It has not been appraised for quality by NHS Evidence staff. (Source: Gastroenterology and Liver Diseases Specialist Library - Small intestine)

This article is not available freely or via NHS Athens username and password. NHS professionals are advised to check their local library to access the fulltext of this journal. Note: This article has been included in the Specialist Collection as it is a systematic review published in a reputable journal in the field.  It has not been appraised for quality by NHS Evidence staff. (Source: Gastroenterology and Liver Diseases Specialist Library - Diagnostic procedures)